Wellbutrin uk is an antidepressant medication typically taken in tablet form. However, it has also been marketed as a smoking cessation medication. It works by reducing the symptoms associated with nicotine withdrawal while it can also reduce the cravings for nicotine that tend to come with cessation.
For those prescribed bupropion to help them quit smoking, a typical course lasts up to twelve weeks. Most people will be ready to quit cigarettes completely between one and two weeks after taking regular bupropion.
Bupropion is a unicyclic aminoketone antidepressant. It can be prescribed on its own to help in the treatment of depression, but it is also sometimes prescribed as an add-on medication for patients not responding as expected to other antidepressants such as SSRIs (selective serotonin reuptake inhibitors).
It is favourable to other antidepressants in terms of reduced side effects such as sleepiness, weight gain, and sexual dysfunction. Moreover, as it is a nicotinic antagonist (blocks nicotinic acetylcholine receptors in the brain), it is suitable for use in the treatment of nicotine addiction.
History of wellbutrin uk
Bupropion was first manufactured in 1969 by the pharmaceutical company that is now known as GlaxoSmithKline. The company was granted the patent in 1974 and eleven years later the drug was approved for use as an antidepressant. It was marked under the brand name Wellbutrin.
However, one of the side effects of bupropion was an increased risk for seizures, which led to the drug being withdrawn in 1986. It was found that the increased risk for seizures was dependent on the dose and so bupropion was re-introduced in 1989, this time with a lower maximum advised dose.
In 1997, wellbutrin uk was approved for use as a smoking cessation medication, marketed under the brand name Zyban for this purpose.